"I COULD NOT SEE THE SUN FOR MORE THAN TWO YEARS" – A LITTLE BOY IN PRISON/SOLITARY TOLD" WISH THAT NO CHILD HAS TO LIVE IN SHADOW! Photo pebbles foto – Bing images

Archive for November, 2017

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DOUBLING UP A normal female mouse embryo (left) has only female reproductive tissue, called the Müllerian duct (pink). Removing a protein called COUP-TFII causes a female mouse embryo (right) to develop both the female duct and male tissue called the Wolffian duct (blue).


DOUBLING UP A normal female mouse embryo (left) has only female reproductive tissue, called the Müllerian duct (pink). Removing a protein called COUP-TFII causes a female mouse embryo (right) to develop both the female duct and male tissue called the Wolffian duct (blue).

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Share this article https://www.dailykos.com/stories/2017/11/23/1718065/-Study-Embryos-kill-off-male-tissue-to-become-female-overturning-decades-of-scientific-consensus?detail=emaildkre

Add a new ingredient to the sugar, spice and everything nice needed to make girls. Tina Hesman Saey, Molecular Biology, Senior Writer for Science News
A fascinating article in Science News overturns the decades long consensus that females are the ‘default’ sex in mammals. Science News reports on new research that challenges the 70 year old scientific consensus . Instead, they say, “female reproductive organs is an active process that involves dismantling a primitive male tissue called the Wolffian duct”.

A protein called COUP-TFII is what is necessary to eliminate male reproductive tissue from female mouse embryos according to the scientific article. The researchers findings were published in the Aug. 18, 2017 Science.

Tina Hesman Saye writes on the new research:
In males, the Wolffian duct develops into the parts needed to ejaculate sperm, including the epididymis, vas deferens and seminal vesicles. In females, a similar embryonic tissue called the Müllerian duct develops into the fallopian tubes, uterus and vagina. Both duct tissues are present in early embryos.
A study by French endocrinologist Alfred Jost 70 years ago indicated that the testes make testosterone and an anti-Müllerian hormone to maintain the Wolffian duct and suppress female tissue development. If those hormones are missing, the Wolffian duct degrades and an embryo by default develops as female, Jost proposed.
That’s the story written in textbooks, says Amanda Swain, a developmental biologist at the Institute of Cancer Research in London. But the new study “demonstrates that females also have a pathway to make sure you don’t get the wrong ducts,” says Swain, who wrote a commentary in the same issue of Science.
Testing Jost’s hypothesis wasn’t what reproductive and developmental biologist Humphrey Yao and colleagues set out to do. Instead, the researchers wanted to learn how tissues on the outside of the early ducts communicate with the tubes’ lining, says Yao, of the National Institute of Environmental Health Sciences in Research Triangle Park, N.C.
The COUP-TFII protein is produced in that outer layer, and Yao suspected it was involved in talking with the lining. The researchers blocked the communication in early female mouse embryos’ reproductive tissue by removing the gene that produces COUP-TFII.
To the team’s surprise, the Wolffian duct remained in the female mice along with the female Müllerian duct. That shouldn’t happen, according to the textbooks. “We were just scratching our heads,” Yao says.
Searching for an explanation, Yao and colleagues first tested whether removing COUP-TFII changed the ovaries to produce testosterone like testes do. Testosterone could feed the male tissue and allow it to persist, the researchers thought.
“No, the ovary is just like an ovary. There’s nothing wrong with it,” Yao says. “We were just shocked. This can’t be happening.” Further experiments demonstrated that no stray testosterone was responsible for the male tissue sticking around.
Instead, COUP-TFII appears to be the foreman of a biochemical wrecking crew that demolishes the Wolffian duct in females. Without the protein barking orders, the demolition crew is idle and the male duct isn’t torn down. Signals that trigger COUP-TFII production and activity aren’t yet understood.


‘I asked to go to jail, rather than stay homeless’ “THERE ARE LIVES; UNBEARABLE FOR ONE PERSON, sickness, poverty, mental illness, isolation – THOSE WE MUST HELP NOT JAILING!



‘I asked to go to jail, rather than stay homeless’
By Andy Smythe
Victoria Derbyshire programme

 

Bradley’s anti-social behaviour order prevents him from “loitering” near businesses
Banned from begging and sleeping in shop doorways in Middlesbrough, Bradley Grimes asked the judge in court to send him to prison rather than leave him homeless. What effect did it have?
“All they’ve done is placed an anti-social behaviour order on me to try and stop me from begging. But I have to in order to survive,” Bradley Grimes tells the BBC’s Victoria Derbyshire programme.
He became homeless after leaving the care system aged 17.
With autism and, in his own words, the mental age of a “young child”, he was unable to find work and frequently turned to begging – asking passers-by for food and money at the side of a busy street.
But this led to Middlesbrough Council giving him an anti-social behaviour order, or Asbo.
It came with a condition banning him from “loitering” outside business premises.
Bradley says it prevented him from “basically sitting outside a shop” and sleeping in doorways for warmth, and meant he was continually arrested.
“CCTV picks you up and they dispatch either the police or street wardens. If police come, you’re arrested,” explains Bradley, who’s now 23.
He says he attracted the authorities’ attention for sitting rested against a bus stop.

Bradley says he was once arrested while sitting rested against this bus stop
“It got to the stage where they were locking me up once or twice a day, for a period of a few months.
“I was in [prison] pretty much all weekend, near enough every weekend.
“I can’t even sit on a public bench without being locked up. I have to keep moving.”
Frustrated at his situation, he decided to seek help – albeit in an unusual form.
When in court, charged with breaching a four-month suspended jail sentence – something he admitted to doing – he asked the judge to send him to prison.

This is where Bradley says he often used to sleep, just off the side of a busy road
He hoped it would pave the way to him being found suitable accommodation.
“That’s the last option I had, that I could think of,” he explains.
The judge was sympathetic, and was reported in October this year as saying that “essentially we are locking up a homeless man for being homeless.
“I want him housed somewhere so that his welfare can be looked after.
“It is not good enough for the authorities to turn around and say that it is somebody else’s problem.
“If I were to let you go today the chances are that you would be sitting on a seat or sleeping in a shop doorway and you will be locked up again.”
By November, Bradley was released – with supported accommodation made available.
He had lived in the same building previously, but says he was told to leave after cannabis was found in his room.
Bradley has also had problems with Class A drugs, which he says he used “to take the pain away”.
This time he says he is determined to live clean, and has avoided drugs since his release.
‘Impossible to cope’
Bradley says life can still be tough. In fact, he believes that because of his autism, it was simpler in prison.
“You don’t have to worry about anything in [jail].
“[Whereas on the outside] it’s impossible for me to cope on my own, because I’m bad with things like budget and money.”
When Bradley left prison in Durham, he had just £17 to his name – most of which he used for the train journey back to Middlesbrough.
He has now applied for benefits, which he is waiting to receive, but says his lack of funds over time has had a significant impact on his health.
Bradley has a brain tumour – and suffers with epilepsy and a heart murmur – but says he cannot afford to travel to the specialist cancer centre in Newcastle for treatment…….http://www.bbc.com/news/uk-42057173#_=_


Joe Biden’s disturbing behavior around kids Dec 6, 2016 “Joe Biden can’t keep his hands off of Senators’ children at the swearing in ceremony.” Video


Must see YouTube compilation of Joe Biden’s disturbing behavior around kids YouTube video ^ Posted on 11/17/2017, 7:51:25 AM by ETL dave davidson Published on Dec 6, 2016 “Joe Biden can’t keep his hands off of Senators’ children at the swearing in ceremony.”

https://www.youtube.com/watch?v=DwXweiRjckI

via Must see YouTube compilation of Joe Biden’s disturbing behavior around kids YouTube video ^ Posted on 11/17/2017, 7:51:25 AM by ETL dave davidson Published on Dec 6, 2016 “Joe Biden can’t keep his hands off of Senators’ children at the swearing in ceremony.” https://www.youtube.com/watch?v=DwXweiRjckI — BLOGGIN’ BAD w/ Gunny G! ~ HEY! NO MORE PC, REMEMBER? ~AMERICA CANNOT BE GREAT AGAIN UNTIL THE STAIN, STIGMA, STENCH AND SHAME OF “THE PRINCE OF FOOLS” IS OFFICIALLY AND FINALLY BROUGHT TO JUSTICE, AINOs (AMERICANS IN NAME ONLY) EXPOSED, AND THE SWAMP FLUSHED! -POTUS .45 TRUMP COCKED and LOCKED!…..-ONE RIGHTEOUS MAN–IF WE CAN KEEP HIM! ~ Illegitimi non carborundum…


Illegal alien raped/impregnated 14-year-old stepdaughter for anchor baby



Sexgate: Actor Tom Sizemore accused of molesting 11-year-old girl — Fellowship of the Minds


The parents and others involved in the movie knew about this and did nothing. NOTHING. After all, they had a “fiduciary responsibility to the movie. What a cesspool Hollyweird is. From Hollywood Reporter: Actor Tom Sizemore was told to leave a Utah film set in 2003 after an 11-year-old actress told her mother that he […]

via Sexgate: Actor Tom Sizemore accused of molesting 11-year-old girl — Fellowship of the Minds


via Community remembers murdered Sumter Co. girl, 16, while cops search for her killer — WFLA|Children in Shadow


SUMTER COUNTY, Fla. —It was an emotional night for the loved ones of a local teen who was found dead last week. Loved ones gathered to remember Aleaya Jackson a week after her death. The community united to remember Jackson. On Wednesday night, her family and friends prayed together. Her classmates stood side by side,…

via Community remembers murdered Sumter Co. girl, 16, while cops search for her killer — WFLA


via Florida school sells bulletproof panels for students’ backpacks — WFLA|Children in Shadow Blog


MIAMI (CNN) – A Miami private school is offering parents an unusual item for sale: bulletproof panels for their kids’ backpacks. The Florida Christian School website has a list of items available for purchase. These include winter wear, red school logo T-shirts and ballistic panels George Gulla, dean of students and head of school security at Florida Christian…

via Florida school sells bulletproof panels for students’ backpacks — WFLA


New Documentary ‘An Open Secret’ Exposes Hollywood Man-Boy Pedophile Ring


An Open Secret

Cliff Kincaid of Accuracy in Media reports that An Open Secret, a new explosive documentary on Hollywood pedophiles opened on Friday night, July 3, 2015, at the Cinema Village at 22 East 12th Street in New York City. On July 17, the film will open in Los Angeles at Laemmle’s Music Hall in Beverly Hills.